Cardioprotective therapy and sodium-hydrogen exchange inhibition: current concepts and future goals.

CARDIOPROTECTIVE EFFECT OF Na/Ca EXCHANGE INHIBITION IN CARDIOPLEGIC ARREST BY SEA0400 by

Synthesis and Characterization of Cation Exchange PVA-g-PAA/PBI sulfone Membrane for the Electrolysis of Sodium Chloride

The reported work is on the preparation and characterization of polyvinyl alcohol -g- Polyacrylic acid (PVA-g-PAA)/ Polybenzimidazole sulfone (PBIs) cation exchange membrane used for the electro dialysis of sodium chloride solution. The polymer syrup has been prepared using the grafting method with the help of polyvinyl alcohol and polyacrylic acid in the presence of water solvent. The polymer ...

Thioredoxin 1 is essential for sodium sulfide-mediated cardioprotection in the setting of heart failure.

OBJECTIVE The aim of this study was to determine whether thioredoxin 1 (Trx1) mediates the cardioprotective effects of hydrogen sulfide (H2S) in a model of ischemic-induced heart failure (HF). APPROACH AND RESULTS Mice with a cardiac-specific overexpression of a dominant negative mutant of Trx1 and wild-type littermates were subjected to ischemic-induced HF. Treatment with H2S as sodium sulfi...

Risk stratification of patients with right ventricular infarction: is there a need for a specific risk score?

H(+) exchange inhibitor eniporide as an adjunct to early reperfusion therapy for acute myocardial infarction. Results of the evaluation of the safety and cardioprotective effects of eniporide in acute myocardial infarction (ESCAMI) trial. J Am Coll Cardiol 2001; 38: 1644–50. [13] Buerke M, Rupprecht HJ, Vom DJ et al. Sodium–hydrogen exchange inhibition: novel strategy to prevent myocardial inju...

BRIEF REVIEWS The Plasma Membrane Sodium-Hydrogen Exchanger and Its Role in Physiological and Pathophysiological Processes

The plasma membranes of most if not all vertebrate cells contain a transport system that mediates the transmembrane exchange of sodium for hydrogen. The kinetic properties of this transport system include a 1:1 stoichiometry, affinity for lithium and ammonium ion in addition to sodium and hydrogen, the ability to function in multiple 1:1 exchange modes involving these four cations, sensitivity ...